KMID : 1134220100300030238
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Hanyang Medical Reviews 2010 Volume.30 No. 3 p.238 ~ p.245
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Eosinophil and Tissue-invasive Parasitic Helminth
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Shin Myeong-Heon
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Abstract
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Eosinophils are primarily tissue resident cells, and play important roles in host¡¯s immune responses and maintenance of chronic infection during infection with tissue-invasive parasitic helminth. Such parasite secretes particular molecules to evade eosinophil-mediated helminthotoxicity. Continuous competition between eosinophil and parasite leads to stable equilibria between them. Recent evidence provides a concept that not only eosinophils contribute to parasite¡¯s survival but also parasite modulates host¡¯s immune response. Therefore, it is important to know complex interrelationship between eosinophil and parasite to understand how gently parasite talk to eosinophils and how carefully eosinophils listen to parasite¡¯s voice. In this regard, this review examin papers about eosinophil-mediated tissue inflammatory responses in response to helminthic parasite.
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KEYWORD
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Eosinophils, Parasitic helminth, Hostparasite interrelationship
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